FYI the last time I was in Vegas we ended up at a hotel called the Vdara. It's right near the strip--they have a covered walkway over to the Bellagio, so the location was right. I got a decent deal on price--all things considered [i.e. Vegas on the weekends near the strip isn't cheap anywhere, and valet/resort fees jacked it even further].
The hotel doesn't have a casino, so you don't have all-night loud craziness going on. In fact, on a Friday and Saturday night, we were able to sleep comfortably without any interruptions. It's a smoke-free property, so there's no odor permeating the ground floor, the hallways, and certainly not the rooms. The rooms were ample-sized, nice and modern, with a little kitchenette, and a nice bathroom. On the main floor there was a little restaurant and bar, a market, a Starbucks, and all the usual amenities of a nice hotel.
In general, I found it a much nicer way to do Vegas than to stay at one of the casinos. It seemed more like the kind of place that someone that was in on business or who was an entertainer in residence would stay.
I was considering it again for my upcoming trip in June, but ended up finding the better deal at the Bellagio and figured you can't exactly go wrong there.