From an Ohio State perspective, last time the Buckeyes were without Liddell, who is probably their best player and Seth Towns, who has slowly gotten more and more minutes. These guys combined for 37 points against Illinois, so having them should make a big difference. The Buckeyes will probably be without Sotos and Walker (#1 and #2 PGs) though who combined for 42 minutes against Purdue in the earlier meeting. I feel a little more confident about the missing PGs, since the Buckeyes were able to navigate the Illini chaos on Saturday.
The Buckeyes have been killing it from behind the arc the last few games, after being pretty awful the first few games of the Big Ten season. I think they're probably somewhere in the middle. If the Buckeyes don't shoot the lights out again, then I think this will be a very tense game and will go down to the wire. Purdue is a team that always seems to play the Buckeyes very tough.