Ohio St leads the all time series 72-12-5.
Indiana dominated the series prior to OSU joining the Big Ten. They played every season from 1901-1905, with Indiana taking all but one, which was a tie.
Indiana won the inaugural Big Ten show down, 7-6 in 1913.
After that it's been pretty much all OSU, with Indiana picking up wins in 37, 43 (Paul Brown's final season), 47, 51 (Woody's first season), 87 (Earle Bruce's final season), and 88 (John Cooper's first season).
Indiana is the only team in the Big Ten that hasn't knocked off the Buckeyes a single time, since the 1980s.