I think we're all pretty injured (Michigan was down 3/4 of its starting DL versus Maryland and lost some depth behind the starters as well; we've also been down our best WR and RB co-starter), but that does sound particularly bad for UW. And they don't seem to be stemming the injury tide on defense.
This is an interesting game for a lot of reasons - for one because we play too seldom in an expanded Big Ten and, for two, because not many ranked teams run offenses like these anymore. It's also impactful for the whole dang season. Wisconsin has a fair strangehold on the West right now. But if they were to lose once or twice, and they do play two games like this one, things get very interesting over there. And for Michigan, I think it's generally noted that they've put 2017 behind them and are better compared to 2016 when the team came a literal inch from the CFP. But these next 3 games (UW, MSU, PSU) determine all of that. They need to go undefeated through these three to stay in the CFP race. However, winning 2/3 keeps them in the race for the East.