This game hasn't been close the past 4 years, and I see no reason to expect anything different this time. Michigan fans will overtake their stadium like they have in 2015 and 2017, just like they do at Rutgers in even years.
Defensively, Michigan just needs to shut down their RBs. They've done that pretty well the past 4 weeks so I don't see why they wouldn't in this game, too. Their passing game isn't very good, and Michigan has shut down better QBs and WRs than they have. Offensively, Michigan will probably just run it for most of the game and pass when they need to.
The biggest question is how quickly Michigan is able to get a big lead. If they can finally play well from the start, they could put in the backups for a good part of the second half, though with the way the second half of the Illinois game went, they might keep the starters in longer than they need to.