Yeah....excluding the two (N) Texas losses, OU still has 3 road losses to 2 home losses. A very small sample size, but over time a 3:2 ratio is a pretty significant difference.
But it's also worth accounting for the quality of the opponent. Ole Miss was loaded last year, albeit an underachieving team. LSU was loaded on offense, though also not without significant problems. Tennessee was sort of in the same boat. South Carolina beat a lot of good teams last year, the main indictment in a home loss mostly being in how bad OU lost. The chances of losing to teams like that is more, no matter where you're playing.