The little village I lived in on the Navajo Rez got their first known case, and it was an employee at the grocery store. Reeeally bad news - this place has only the grocery store, a gas station, and a subway. No other commecial properties at all.
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So they closed the grocery store - the next nearest one is 60 miles away. Of course their first case is someone working at the only social hub that exists there. It's going to get bad.