Ugh, why is this always an issue in these 'what if' scenarios?
You base it on how good the players were. Like in a 0-100 scale, maybe OU's 235 lb left tackle was a 90 out of 100 player. And perhaps OSU's 300 lb guard was an 84 out of 100 player.
Player size, skill and coaching strategies gradually improve and grow over time. The worst team in 2022 would destroy the best team from 1950 if they actually played. That's not what this is about, obviously.