It doesn't really matter where Michigan ends up for the first weekend (none of which would be favorable, though Hartford or San Jose would probably actually be preferable to Columbus with the Michigan fan base in NYC / Boston and the Bay Area), but I certainly hope they're in the DC Regional (not only for selfish reasons, because they'd have the best Michigan turnout here, though Anaheim would be good, too, as evidenced by their games in LA last year).
Also, not that it really matters, but a 1 seed is still a vague possibility if Michigan wins out and Duke, Virginia, and/or Tennessee get upset in the mean time (Gonzaga just won at Saint Mary's so it'd be a shock if they lost in the WCC tournament).... Presuming they remain a two seed, I don't really have a preference about which 1 seed would be in their region. I don't want to see Houston or Texas Tech from the 3-seed, but Purdue and Sparty are the other current 3-seeds on CBSSports.com (but I know that intra-conference rematches are only prevented through the first weekend).