Thinking about run game, it's hard to go against Bijon's teams for UT, but I'm kinda partial to the 2005 iteration. The depth and variation of strengths was quite something on that team. I'm trying to remember them all now, I used to know their names. There were five of them. Jamaal Charles was a great all-around back. Ramonce Taylor, was a speedy little mofo, killer in space. Henry Melton was a short-yardage specialist, a 260+ pounder who, I think, later got moved to DE. Selvin Young was a guy I don't remember much about anymore, but he stands out as one of the five worth remembering, so I assume he was pretty good at something. Can't remember the fifth guy I'm thinking of. Pretty sure there was a fifth, tho. It was a deep and versatile crew, probably made all the more productive by the threat of VY's read-options.
There wasn't a good way to match up Texas' 2005 run game imo. Best option was to wreck the line and stop a play before it really started, but UT's 2005 OL made that rather difficult, and seldom realized. That'd get my pick.