Losing the 4 killer road games (OSU, UM, UW, NW) is obvious. Losing at home to PSU. MSU is probably underdogs in those 5 anyway, so basically, start by losing all the games you should.
Am I overly optimistic in thinking they shouldn't lose more than 1 other (Tulsa, WMU, ASU, Indiana, Illinois, @Rutgers, Maryland)? Going even 5-2 through those would raise serious questions with where the program is, obviously barring another year of major health issues, but we have to be due for good luck there after how bad last year was (losing starting QB, starting RB, both starting WRs, best CB). So maybe 6-6?