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Why was he such a colossal failure at Louisville this time around?

He hired Brian Vangorder as his defensive Coordinator. Dude almost got Brian Kelly fired at ND

That’s the thing - save for this disaster of a season Petrino’s 2nd stint really wasn’t a failure. Not only did he average 8.5 wins/yr, he’s the godfather of growing the Louisville program from C-USA to the Big East to the ACC, and yet in these reactionary times for CFB the Louisville crowd only waited a moment after realizing the recruiting and coordinator situations to turn on him.

they fired him because they want Brohm imo.
Michigan fans should hope Brohm takes the job. Michigan "insider" Sam Webb said on his radio show today that if Brohm goes to Louisville, 5* DL George Karlafatis- a Purdue commit from the state of Indiana- will be going to Michigan. Sam stated it basically as fact. He doesn't really do stuff like that unless he knows something.
Brohm going to Louisville would basically hand deliver a 5* DL recruit to Michigan.

That’s the thing - save for this disaster of a season Petrino’s 2nd stint really wasn’t a failure. Not only did he average 8.5 wins/yr, he’s the godfather of growing the Louisville program from C-USA to the Big East to the ACC, and yet in these reactionary times for CFB the Louisville crowd only waited a moment after realizing the recruiting and coordinator situations to turn on him.

It makes me believe that internally... not everyone agreed with Petrino coming back.   This season is being used to justify those feelings.   

I hope he stays in the BIG.  If I'm purdue, I'm giving $$$ to keep him.   The west is wide open and he's building something.   Frankly, Purdue should be able to outspend Louisville.

Money won't keep him, if he wants to go. Louisville is home. 
Not that I disagree, however. I'd love to see Purdue give him a raise [and devote more money to assistant budgets] in order to show how much we appreciate him reviving our program and that we believe he's worth it. 
But money won't keep Jeff Brohm. Honestly I don't think money is that important to him. He's still driving the same 2004 Honda Accord 2 years into the Purdue job. Money helps, but the decision will ultimately be whether he wants to take on the Louisville job right now. 

Money won't keep him, if he wants to go. Louisville is home.
Not that I disagree, however. I'd love to see Purdue give him a raise [and devote more money to assistant budgets] in order to show how much we appreciate him reviving our program and that we believe he's worth it.
But money won't keep Jeff Brohm. Honestly I don't think money is that important to him. He's still driving the same 2004 Honda Accord 2 years into the Purdue job. Money helps, but the decision will ultimately be whether he wants to take on the Louisville job right now.

from a distance he seems to be a HC who cares as much about his assistants as anything else.   I'd guess that would be important to him.   

Whether he goes or not could depend on his view of the current LV administration.  He might not be so enamored with them as one might think, and that matters, probably more than money.  I presume he is getting paid well at Purdue now, so maybe he goes from $2.5 mil to $6 mil or whatever, it might not be enough to compensate, perhaps maybe.

Or maybe they are thick as thieves and go hunting together, no idea.  And if they hire someone else, there is a good change the position becomes open again in 4 years and in the mean time he might have built something notable at Purdue and be getting offers from "real programs" like even an Alabama.  I don't know what CB wants from coaching.  There is an inherent limit at Purdue and LV both.

Whether he goes or not could depend on his view of the current LV administration.  He might not be so enamored with them as one might think, and that matters, probably more than money.  I presume he is getting paid well at Purdue now, so maybe he goes from $2.5 mil to $6 mil or whatever, it might not be enough to compensate, perhaps maybe.

Brohm is making over $4M guaranteed on a 7-year deal. It looks like it's backloaded somewhat, only $3.8M this year and increasing each year, but it's 7 years for $29M. 
Not sure what other incentives are there above the guaranteed base.
But Purdue definitely didn't cheap out on him. 
Again, for Brohm, I don't think the number matters. If he wants to go to Louisville, they could probably give him equal money to what Purdue is giving him. If he doesn't want to go, $6M IMHO won't do it.