One issue with accelerating to near c to visit some star system is what you need to do when you get there, which is SLOW DOWN, somehow.
You could accelerate at a comfortable 1 G and then decelerate at 1 G for a trip of course, you'd need a while (about a year) to get to about 0.9 c. Then you'd need the same time to decelerate. You could coast in the interim of course.
The second issue of course is providing the force necessary to accelerate at 1 G. There are a few notions as to how, one is the Bussard ram that extracts matter from space around you, then you need a lot of energy to accelerate said matter. Another is using ground based lasers on a solar sail, but then you need something on the other end that works.