I haven't drank much of anything in years, but as I recall, it depended on what it was. There were some vodkas and whiskeys I got a hold of that probably gave me a minor facial expression even if I tried to control it, which I wouldn't have thought to do. There were other bourbons and whiskeys that were pretty smooth and I don't think they made me grimace.
You'd have seen me blanch at any beer I ever drank, because I never liked the stuff and it all tasted like horse piss to me.