Perhaps the BEST B1G Forum anywhere, here at College Football Fan Site, CFB51!!!

Wisconsin can Michigan in 2005 

Also, underrated, Lexington to Knoxville and Charlotte to say Athens Ohio though Virginia and WV

Anybody been on the hwy from Salt Lake City to Reno?  That's got to be THE blandest drive ever.  Why am I even curious?
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Another drive I want to take is from Miami southwest through the southernmost Everglades to the town of Flamingo.  It's GOT to be a weird place.  Extremely isolated, one way in, one way out.

Utah has great drives, even on Interstates.  The section of I 10 north of LV through the Virgin. River canyon is something to see on the way to Zion NP.  There is a drive over Guardian Pass we took one October when leaves were changing ... It is dirt road in parts.

Use to go up to Ontario/Quebec in early/mid September on fishing trips.Georgeous country once you shake the outskirts of Toronto.Lakes Kashwakamak & Nippissing in Ontario.Lac des Quinze,(dammed for hydo electric back in the day part of a river named Outaouais River I believe which was part of the upper Ottowa River)) and Valdor in Quebec.Gently rolling hills,dairy country,small lakes,rivers and meandering streams and country lanes.In Quebec we had a fresh montain spring about 1/4 mile down a path.Damn near crack your teeth and the accompanying brain freeze.Blue berries and black bears.This is some of what we'd see.There were a paper mill or two along the way which aren't real nice

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Beartooth Highway, between the NE gate of Yellowstone NP over to Red Lodge, MT.  That's a great test of driving and spectacular.   

I once hit about a dozen golf balls off of one of the vistas w a friend about 20 years ago, ball just sails and floats off into the abyss, just an amazing area to fish, hike and camp.  My parents are so spoiled to have so many great day trips.

That Beartooth highway is brutal.  I drove that out of Yellowstone in my Z28 and it was crazy.  I remember looking up at the GPS once (very few opportunities to glance at anything other than the road in front of me) and all I saw on the GPS screen was a giant zig-zag line indicating the numerous switchbacks behind me and to come.  

I grew up just down the hill from highway 84 in California, and used to know nearly every curve on the road by heart. I'm still close, but don't drive it as much as when I was a teen.

I've ridden the PCH (Highway 1) from Carmel to San Simeon (Heart Castle) on my bicycle (and I've driven it). It's about as good a century as there is, I think.

Memorable drives for me: Sarasota, FL, to San Francisco, via Madison, with my sister when we were both coming home one summer.

Denver to Madison in a day--my last speeding ticket. When I crossed the Wisconsin river, and saw it was 80 miles to Madison, I thought, "I can be there in an hour!" Police didn't think that was a good idea. 1000 miles in a day by yourself is probably also not a good idea.

Drove San Francisco to D.C. with a girlfriend in college. Best part was through the Smokey Mountains. Alas, Dolly World was closed. /sarcasm (but true story).

San Francisco to D.C., through El Paso, with a great friend when we graduated college was pretty awesome. Didn't have enough time to really see the sights, but it was a great drive. On the way back to El Paso, saw fireworks over Little Rock as I drove into town. That was memorable.

I drove from California to El Paso and back a few times. While it was a bit drab in parts, other parts of the desert were spellbinding.

I used to drive from Tennessee to Chicago to visit college buddies pretty often on Highway 41 (with the Allman Brothers cranked up)--once or twice I took the interstate (57).

In college, drove from Madison to D.C., through State College, then stopped to watch the Badgers upset the Nittany Lions on the way back. That was pretty cool.

I-80 is pretty boring through most of the midwest. The stretch from Salt Lake to Reno is brutal.

SFIrish and I drove from San Francisco to Salt Lake, then up through Idaho to Helena, MT, and Glacier, then west through Couer D'Alene to Seattle, then Portland, the redwood forests on the California coast, and back to San Francisco. That was a pretty cool trip. Nearly cooked our brakes coming from Tahoe down to Reno on back roads, nearly ran out of water backpacking in Idaho because the rivers were intermittent (not shown on map), nearly got caught in a wildfire in Glacier while backpacking (when we came back to our truck, there was a note asking us to check in with the ranger on our way out, and in the parking lot were only fire vehicles; when we got to the ranger station, they told us we were literally the last people out--we had been blissfully ignorant). Went to the other side of the park, but could only go halfway on Going to the Sun because of the fires.

Nearly got caught in a tornado in Texas on my way from Houston to Centerville. Had some realizations about the importance (or lack thereof) of work that day.

When you take I 75 south it goes over a large mountain as soon as you cross into Tennessee. But if you jump off at the first exit there is an alternate route that takes you along the river, through the woods, alongside a really crazy railroad line, and then you can hop back onto the freeway at the other end of the mountain at a giant lake in a town called Carreyville, iirc. Great place to spend the night if you are driving from Ohio to Atlanta and don't want to do the whole trip in one day.