I've mentioned this before, but IF you are blessed one year with higher income than is typical, look into setting up a Charitable Fund, it's pretty easy and doesn't incur fees (a tiny amount). Then you can make future charitable donations from said fund.
And it's tax deductable in the year you fund it if you find more than your standard deduction (which today is pretty high).
$50,000 would do it, for most, more if you can manage of course. Then you can donate however you want without worrying about not having a tax deduction.