Just from the Jacksonville area the past 25 years:  Brian Dawkins, Derrick Henry, Tim Tebow, CJ Spiller, Laremy Tunsil, Lito Sheppard, Leon Washington, Patrick Sapp.  
The Tampa/St. Pete area produced Peter Warrick, the Pouncey twins, Darren Howard, Jerome Brown, Ted Washington, Ray Lewis, Rodgers-Cromartie, Tommie Frazier, Aaron Murray, Travis Henry, Dexter McCluster, Michael Jenkins, and Vernon Hargreaves III.
Maybe I just respect the panhandle more, idk.  I do love you pretending this hypothetical, "what-if" matchup has a factual answer, though.  It's adorbs.
Haven't even mentioned Emmitt Smith, Deion Sanders, or Derrick Brooks yet, either.  Or Warren Sapp, Chris Johnson, Edgerrin James, Danny Wuerffel....
Ft. Myers area - Jevon Kearse, Phillip Buchanan, Sammy Watkins, Terrence Cody...even got a kicker:  Martin Gramatica. 
Elsewhere:  Duante Culpepper, Nate Newton, Jason Elam (another kicker!), LeRoy Butler, Jack Youngblood, Wilbur Marshall....