First of all, all of these outcomes are <1% chance of success, so it's not a great opportunity to find an inefficiency here. None of it'll work, so who cares?
But as a fun exercise, the screen people are forgetting something: the guy with the ball is much faster than anyone blocking for him.
In prevent defenses, that guy can't outrun anyone on the defense, as they're deep and coming up to the ball-carrier.
So that Raghib Ismail inside tunnel screen isn't going to work. Ismail is past his blockers and/or faster than them, AND 6 guys are back deep between him and the end zone.
When that play is used in a normal situation, he just has to split 2 DBs, not 6 guys laying in wait.
We all remember Flutie and we all remember THE BAND IS OUT ON THE FIELD, but the most normal-looking, too-deep-for-a-hail-mary success story was LSU's miracle vs Kentucky.
They ran a normal deep pass play, threw it deep, and the receiver's bobbling of the ball got him past the prevent guys and on into the end zone.
I think that might be the best bet, because it's neither a hail mary nor a Cal-Stanford ending.