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Topic: CRISPR and AI

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MikeDeTiger

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Re: CRISPR and AI
« Reply #154 on: February 25, 2026, 03:37:37 PM »
Quote from: utee94 on February 25, 2026, 03:33:07 PM
That's good news because almost nobody else can anymore.

Next, it's gonna learn Fortran.
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utee94

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Re: CRISPR and AI
« Reply #155 on: February 25, 2026, 03:40:48 PM »
Quote from: MikeDeTiger on February 25, 2026, 03:37:37 PM
Next, it's gonna learn Fortran.
AI-- reviving computer science one antiquated, dead language at a time!

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utee94

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Re: CRISPR and AI
« Reply #156 on: February 25, 2026, 03:45:25 PM »
When I was an undergrad in electrical engineering at UT, the computer language they were teaching was Pascal.  Not only Pascal, but Think's Lightspeed Pascal on Apple Macintosh, which in the world of electrical engineers, has been used in practice by, well, nobody.  Ever.  I don't even think Apple ever used Pascal on their own hardware.

Fortunately for me

a) I already knew Pascal from my high school Comp Sci courses so the course was an easy A and
b) I interned for a company that required me to learn C and C++ on SunOS/Solaris Sparcstations



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Honestbuckeye

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Re: CRISPR and AI
« Reply #157 on: February 25, 2026, 03:45:31 PM »
Quote from: utee94 on February 25, 2026, 12:43:40 PM
Yet another reason not to move to Austin!

Just kidding, that article outlines a grim projection to be sure.

i have a lot of thoughts about this, hopefully will have some time to formulate and write them down.

I will say that even if the overall premise ends up being 100% correct, and that AI and agentic AI advance so rapidly over the next two years that this could come to fruition within that timeframe... it's still not going to happen within that timeframe.  For one simple reason-- hardware scarcity and hardware shortages.  @MikeDeTiger 's concerns due to the rapidly increasing price of memory over the past couple of years-- a result of tremendous shortages for that category of products-- doesn't just apply to that one commodity.  It's hitting almost all hardware commodities across the board.  CPUs, GPUs, memories, other various ICs-- and since the manufacturing leadtime for silicon is so long, there won't be resolution for it within the next couple of years. 

That doesn't mean the issues aren't realistic, it just means the timeline isn't quite as immediate.
I happen to agree with you- 100%.

Kind of crazy how an article like that can cause banks, as one example, to lose 4-10% of their value in 1 day. 
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MikeDeTiger

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Re: CRISPR and AI
« Reply #158 on: February 25, 2026, 03:50:27 PM »
Quote from: utee94 on February 25, 2026, 03:40:48 PM
AI-- reviving computer science one antiquated, dead language at a time!

It's all fun and games until Skynet builds the T-800 to run on Turbo Pascal and nobody knows how to code the 'off' switch!
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utee94

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Re: CRISPR and AI
« Reply #159 on: February 25, 2026, 03:53:33 PM »
Quote from: MikeDeTiger on February 25, 2026, 03:50:27 PM
It's all fun and games until Skynet builds the T-800 to run on Turbo Pascal and nobody knows how to code the 'off' switch!
I think you've just uncovered AI's master plan.  Code itself into such crazily antiquated forms of programming that no living human will have the means of stopping it or turning it off.

Final BOSS level-- TI Logo. 







iykyk
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MikeDeTiger

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Re: CRISPR and AI
« Reply #160 on: February 25, 2026, 04:00:41 PM »
Quote from: utee94 on February 25, 2026, 03:53:33 PM

iykyk

idkbifo


Quote from: utee94 on February 25, 2026, 03:53:33 PM
I think you've just uncovered AI's master plan.  Code itself into such crazily antiquated forms of programming that no living human will have the means of stopping it or turning it off.

Final BOSS level-- TI Logo.

Ironically, AI will then be easily thwarted by elementary school kids from the 1970's.  I did NOT see that coming. 
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utee94

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Re: CRISPR and AI
« Reply #161 on: February 25, 2026, 04:03:26 PM »
Quote from: MikeDeTiger on February 25, 2026, 04:00:41 PM
idkbifo


Ironically, AI will then be easily thwarted by elementary school kids from the 1970's.  I did NOT see that coming. 
I think I've found the premise for my next 3/4 finished novel!

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MikeDeTiger

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Re: CRISPR and AI
« Reply #162 on: February 25, 2026, 05:50:21 PM »
Quote from: iahawk15 on February 25, 2026, 01:42:01 PM
I will say upfront that I have not used Claude Code or dabbled with mcp servers AT ALL yet. However, as a sideline observer via twitter and some other dev gathering points, I'm confident this could be built with Claude Code as long as your SaaS has an API to get the data programatically.

As a somewhat experienced user of ChatGPT Pro and Gemini Pro, very skeptical of those models getting this done.

That said, Gemini built me a Gravity Forms --> CE Broker reporting script with very minor edits required.

Any thoughts on Grok?  Last July I shared something about Grok 4 crushing the ARC test, shattering previous metrics.  BUT.....I didn't verify that info was true, and....last July could be a lifetime ago for AI models.  

I've used the free version of Grok a little bit.  Seemed fine, for what I did with it at the time.  I've used the free version of ChatGPT a fair bit.  It let me down in a serious way today, but, that's nothing unusual.  The paid version I'm sure is better, but if Grok is still really good, I might be willing to give the $30/mo. plan a test run.  One thing I know....ChatGPT is incapable of teaching/solving problems for a beginner using Adobe Illustrator....but boy it sure does think it's giving the right answers, and it's really optimistic each time it fails that its next output is going to be what solves everything for me.  
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Gigem

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Re: CRISPR and AI
« Reply #163 on: Today at 07:27:51 AM »
I’ve noticed that Chat GPT will always pretend it knows the answer and feed you bull shit essentially forever. If you prod it enough it will finally admit that it’s just not good at certain tasks, which I think would be pretty important information to have before it tries to solve a problem. 

Like, yo, Gigem, I’d love to help you with this issue but fair warning, this is something that I’m not great at. 

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FearlessF

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Re: CRISPR and AI
« Reply #164 on: Today at 08:05:57 AM »
too much ego
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"Courage; Generosity; Fairness; Honor; In these are the true awards of manly sport."

iahawk15

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Re: CRISPR and AI
« Reply #165 on: Today at 09:26:48 AM »
Quote from: MikeDeTiger on February 25, 2026, 05:50:21 PM
Any thoughts on Grok?  Last July I shared something about Grok 4 crushing the ARC test, shattering previous metrics.  BUT.....I didn't verify that info was true, and....last July could be a lifetime ago for AI models. 

I've used the free version of Grok a little bit.  Seemed fine, for what I did with it at the time.  I've used the free version of ChatGPT a fair bit.  It let me down in a serious way today, but, that's nothing unusual.  The paid version I'm sure is better, but if Grok is still really good, I might be willing to give the $30/mo. plan a test run.  One thing I know....ChatGPT is incapable of teaching/solving problems for a beginner using Adobe Illustrator....but boy it sure does think it's giving the right answers, and it's really optimistic each time it fails that its next output is going to be what solves everything for me. 
Again, only regurgitating sentiment from dev twitter / reddit, but Grok is not regularly mentioned as a serious player. For dev, Claude Code is the standard, but the new Codex model is getting very good reviews.

IMO, if you're going to pay for one, try Claude first.

I've got 5-6 Claude YT videos queued up to hopefully get up to speed on all things Claude this week.
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MikeDeTiger

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Re: CRISPR and AI
« Reply #166 on: Today at 09:36:04 AM »
Quote from: Gigem on Today at 07:27:51 AM
I’ve noticed that Chat GPT will always pretend it knows the answer and feed you bull shit essentially forever. If you prod it enough it will finally admit that it’s just not good at certain tasks, which I think would be pretty important information to have before it tries to solve a problem.

Like, yo, Gigem, I’d love to help you with this issue but fair warning, this is something that I’m not great at.


Yeah, stuff like that has to be baked in to the model sort of as an addendum, and I don't know how much of that happens in the development of these things.  The problem is, AI can't tell you it's not good at something because it doesn't know if it's good at something or not.  It doesn't know anything.  To the extent it would say anything like that, it would have to be riffing on training data where other people already wrote that ChatGPT is not good at something, and even then, that's probably a low-probability token that's not likely to appear.  

I know they do mods to the models on top of training.....things like making sure it doesn't say offensive things, dangerous things, stuff considered inappropriate or immoral, etc.  I think getting it to tell you "Actually, this isn't my strong suit, maybe just try Stack Overflow" would have to be part of that.  
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MikeDeTiger

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Re: CRISPR and AI
« Reply #167 on: Today at 09:39:53 AM »
Quote from: iahawk15 on Today at 09:26:48 AM
Again, only regurgitating sentiment from dev twitter / reddit, but Grok is not regularly mentioned as a serious player. For dev, Claude Code is the standard, but the new Codex model is getting very good reviews.

IMO, if you're going to pay for one, try Claude first.

I've got 5-6 Claude YT videos queued up to hopefully get up to speed on all things Claude this week.

I guess this is a elementary question (just pretend this is the No Stupid Questions thread).....is what I'm talking about considered dev work?  I'm not really trying to code anything or build software, exactly.  I want it to use software in an intelligent and goal-oriented way to mimic how I'd use it and spit out a complicated, specific dashboard.  

I mean, actually, I don't want it to do that, because if it can, then we're all screwed.  But in the spirit of HB's post, I need to start finding out the uses and limits of this stuff.  
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