Yes, in the race to win the West, Iowa is hardly ever hurt by its record against the east. In fact the main reason it won the West in 2021 was its 3-0 record against the East in 2021.
Iowa does not win the West more often because Iowa can not consistently beat Wisc, NW and Purdue. Iowa's record against the West since 2014
Wisc 2-6
NW 4-4 (but 0-2 the 2 years NW won the west)
Pur 4-4 (only 1-4 vs Jeff Brahm since 2017)
Minn 7-1 (7-0 since 2015)
Neb 7-1 (7-0 since 2015)
ILL 8-0