Based on the past two games, Michigan might not really even try to run the ball much, and I actually think that makes sense, and is arguably how they should've been playing all year. Michigan's OLine is very good at pass blocking, so it's just a matter of Patterson getting rid of it quickly enough, which he is getting better at of late. Michigan is going to need big plays on offense, and you're not going to get that from any of the RBs.... OSU has a better secondary than most teams Michigan has faced, but I'll take my chances there instead. The weather forecast does look somewhat ugly, but Michigan did well last week and even did okay against Notre Dame whereas in previous years, the passing game would be awful if there was any precipitation.
Ohio State's offense concerns me, for sure, but compared to last year, Michigan's defense is making much better and quicker adjustments. Indiana scored TDs on its first two possessions and so did Sparty on its first, and then they were shut down the rest of the way. ND didn't score until the second half when the game was no longer really in doubt. Penn State did score early but got shut down in the second half.... I think they'll slow down the OSU running game well enough, but it's the passing game that concerns me, but the weather is a huge variable there, too, of course.
It goes without saying that turnovers are going to be very important. Fortunately, Michigan has been much better at not committing them along with creating them the past few weeks, whereas Ohio State had some bad ones last weekend.