OSU is obviously one program that will have elite skill level players routinely no matter who they lose with few exceptions. Even a "decent" RB should do well at OSU if he doesn't fumble much. Their season probably hinges on the Penn State game, but going 11-1 is still good enough so long as PSU loses two of course (if that is their one).
Maybe they stumble vs MSU or something, that shouldn't really matter.
Will they find another "game changer" on defense? Maybe.